0544 Polysomnography characteristics of children with obesity: A single center retrospective study

Abstract Introduction The constellations of symptoms known as obstructive sleep apnea (OSA) results from either partial or complete airway obstruction during sleep. This affects effective gas exchange and disrupts architecture resulting in fragmentation with downstream immediate long-term adverse effects. Obesity is a significant risk factor childhood OSA, especially post-pubertal children. Obese/overweight children have been found to significantly higher rates OSA than their normal-weight counterparts, independent tonsillar size. Polysomnography characteristics (PSG) comparing obesity without comorbidities (Hypertension, Diabetes Pre-diabetes) has not previously described. Methods Retrospective analysis 190 obese (BMI>95th centile), age between 7-18 years AHI ≥5/hour met the criteria for data analysis. Clinical, demographic PSG parameters co-morbidities were compared using Wilcoxon rank sum test. Correlation (Spearman non-parametric) regression model was employed explore associations characteristics. Results Majority (mean BMI 33.2) had mild no difference two groups. Children older BMI. There groups after adjusting z scores. increased increasing centiles. In our model, peak ETCO2 associated Black race, AHI, rhinitis inversely asthma. Peak Oxygen at baseline, nadir desaturation duration correlated BMI-centiles. Older lower O2 nadir. race desaturation, supine arousal index. Supine rhinitis. Average heart rate when awake, NREM REM Conclusion study, majority comorbidities. average ETCO2, AHI. suggesting synergistic effect obesity. Support (If Any)